Volume 10, Issue 1, March 2016

Dr. Schwartz completes distinguished term as Chairman of the Department of Pediatrics

Alan L. Schwartz, Ph.D., M.D., the Harriet B. Spoehrer Professor of Pediatrics, the Pediatrician-in-Chief of St. Louis Children’s Hospital, and the Executive Director of the Children’s Discovery Institute, will step down as Chairman of the Department of Pediatrics at the end of March.  Dr. Schwartz has served as Chairman of the Department since 1995.

Dr. Schwartz received is B.A., Ph.D. and M.D. from Case Western Reserve University.  He completed research fellowships at the University of Helsinki, Case Western Reserve University, and the University of Auckland before completing his residency in pediatrics at Children’s Hospital Medical Center in Boston.  He then completed a fellowship in Hematology/Oncology at the Children’s Hospital Medical Center and Dana-Farber Cancer Institute in Boston. He joined the pediatric faculty at Harvard Medical School in 1979 where he rose to the rank of Associate Professor in Pediatrics.  In 1986, he joined the faculty at Washington University School of Medicine as a Professor of Pediatrics and also as Director of the Division of Pediatric Hematology/Oncology.  He served as the Division Director until becoming Chairman in 1995.

Dr. Schwartz has had a distinguished career in academic pediatrics.  He has published over 200 manuscripts in leading scientific journals and has played a leadership role in numerous national and international organizations including the National Institutes of Health, the Doris Duke Charitable Foundation, the March of Dimes, the Pediatric Scientist Development Program, and the American Pediatric Society (President 2013-2014).  He has received numerous awards and honors during his career including Alpha Omega Alpha, the Society for Pediatric Research Young Investigator Award, the Society of Pediatric Research E. Mead Johnson Award, and the Distinguished Faculty Award from Washington University School of Medicine.  He was elected to the National Academy of Medicine in 1999 and elected a Fellow of the American Association for the Advancement of Science in 2007.  He received an honorary degree from the University of Helsinki in 2010.

During Dr. Schwartz’s tenure as Chairman of the Department of Pediatrics, the clinical and research missions of the Department have witnessed substantial growth.  Among the highlights of his tenure were the completion of the McDonnell Pediatric Research Building and the innovative reorganization of pediatric research around themes.  Dr. Schwartz was also a driving force behind the creation of the Children’s Discovery Institute and its investment in research to understand the biology of pediatric diseases and the development of treatments through its unique collaboration between clinicians and investigators.  Dr. Schwartz has also been instrumental in the development of physician-scientists both at Washington University and nationally through his mentoring of investigators and his leadership within the Pediatric Scientist Development Program. 

The Office of Faculty Development would like to thank Dr. Schwartz for his support and encouragement of our mission to provide programs for faculty development and faculty satisfaction.    



Emke Recipient of Samuel R. Goldstein Leadership Award in Medical Student Education

Amanda Emke, MD Assistant Professor, Pediatric Critical Care Associate Fellowship Director, Pediatric Critical Care Course Master, Pre-Clinical Pediatrics

“Recipients of the Distinguished Faculty Awards and Goldstein Leadership Awards have made profound contributions to the School of Medicine in patient care, education, research and community service, touching the personal and professional lives of so many people in so many ways. It’s an honor knowing and working with them and seeing what they bring to our academic community,” said David H. Perlmutter, MD, executive vice chancellor for medical affairs and dean of the School of Medicine.

Call for Applications 

Doris Duke Fund to Retain Clinical Scientists Program at WUSM

The Doris Duke Fund to Retain Clinical Scientists (DDFRCS) Program assists with the needs of junior or mid-career faculty facing extraprofessional demands.  The DDFRCS also provides broad-based education to raise awareness, and implement new interventions, resources and mentoring to support junior faculty facing extraprofessional challenges.  Please click for details.  Letters of Intent and Applications Due:  April 1, 2016


Dietary Link to Stunted Growth Identified

Worldwide, an estimated 25 percent of children under age 5 suffer from stunted growth and development. The most visible characteristic is short stature, but the effects of stunting are far more profound: The condition prevents children from reaching their cognitive potential; makes them more susceptible to illness and infection; and shortens their life spans.

While nutritional interventions have had a significant impact on reducing deaths from acute malnutrition, their impact on stunting is modest, leaving researchers vexed and the enduring problem of stunting largely unanswered.

But now, a team of researchers led by senior author Mark J. Manary, MD, at Washington University School of Medicine in St. Louis, has found that inadequate dietary intake of essential amino acids and the nutrient choline is linked to stunting. That knowledge may unlock the door to new approaches to treat the debilitating condition.

The findings are published online in EBioMedicine.



Gut Microbes linked to Necrotizing Enterocolitis

Analyzing gut bacteria in premature infants, Philip Tarr, MD, the Melvin E. Carnahan Professor of Pediatrics and Barbara Warner, MD professor of pediatrics, have shown that babies who developed necrotizing enterocolitis had a different mix of microbes in their intestines than babies who never developed the condition. The diverging microbial communities were observed before any evidence of disease, suggesting it may be posible to prevent the illness by keeping the balance of gut microbes in check.



Funded Awards

PI Award Title
Magee, J.
Gabrielle's Angel Foundation
Development Context and Germline Variation in Infant Leukemogenesis
Manary, M. US Aid Food Aid Quality Review Phase II
Rosenbaum, J. SLCH Foundation
Pediatric Advanced Care Team
Spinella, P. Entegrion, Inc./DoD PdPlex Xa Reversal
Storch, G. CDC/City of ST. Louis HIV Prevention Intervention for Targeted Populations at Risk
Tarr, P BJH Foundation/Clinical Translation Research Grant Program Rapid Bacterial Community Characterization in the Infant Gut
White, N. NIH/U01
17/22 Diabetes Prevention Program Outcomes Study (DPPOS) Phase 3-Research Project



Faculty Development

April Faculty Breakfast

Date: April 15, 8:00 am-9:15 am

Location: NWT8C

Topic: Delivering Effective Presentations

Presenter, Farzana Chohan, Toastmasters

RSVP Required

AWN Spring Dinner - May 5, 2016

Please join us at Bar Italia for AWN award presentations and guest speaker Katrina Armstrong, Chair of the Department of Medicine and Physician-in-Chief at Massachusetts General Hospital. Wine and mingling at 6 and dinner at 6:30 will be followed by the awards and speaker.

To register and make your payment click HERE.

For questions about the event contact Mini Tandon (tandonm@psychiatry.wustl.edu). For questions about payment contact: rivera_k@kids.wustl.edu.


Office of Faculty Development

Brian Hackett, MD, PhD, Director

Bess Marshall, MD, Associate Director

Janet Braun, Program Coordinator







Michael Harris, MD, PhD, is promoted to Professor of Pediatrics in the Division of Newborn Medicine.  After Dr. Harris completed his BA, MSc, PhD, and MD at St. Louis University, he came to Washington University for his Pediatrics Residency and Fellowship in Newborn Medicine.  He joined the faculty after his fellowship. As a faculty member, he has served as an important liaison between the pediatric and obstetrical services in the medical center.  He has been instrumental in the development of guidelines and programs that ensure a smooth transition between antenatal care and postnatal care.  He serves as Medical Director of the Barnes Special Care Nursery and Chair of the Delivery Room Quality Improvement Committee at Barnes-Jewish Hospital.  He is active in a number of hospital committees including the Joint Practice Committee of the St. Louis Children’s Hospital NICU, the Barnes Health Information Management Committee, the HIV Perinatal Work Group, the Congenital Cardiac Heart Disease Screening Committee, and the Woman and Infant Clinical Operations BJC Healthcare Committee.  

Joshua Rubin, MD, PhD, is promoted to Professor of Pediatrics in the Division of Hematology and Oncology.  Dr. Rubin graduated from Yale with a BS in Biology then moved to Albert Einstein College of Medicine where he completed an MSc and a PhD in Neuroscience and an MD.  He then served his residency in Pediatrics at Boston Children’s Hospital and Fellowship in Pediatric Hematology and Oncology at Dana Farber Cancer Institute and Boston Children’s Hospital, after which he joined the faculty of Harvard Medical School, Children’s Hospital of Boston, Dana Farber Cancer Institute.  Washington University was fortunate to recruit him in 2003 to the Department of Pediatrics with joint appointments in the Department of Neurology and Anatomy and Neurobiology, where he has taken several leadership roles including Co-Director of the Pediatric Neuro-Oncology Program, Co-Leader of the Developmental Biology and Cancer Program at the Siteman Cancer Center, and Co-Leader of the Solid Tumor Therapeutics Program.  His research program identified the chemokine CXCL12 and the chemokine receptor CXCR4 as regulators of brain development and contributors to progression of cancer, leading to the development of clinical trials of CXCR4 antagonists as therapy for brain tumors.  In addition, his lab studies the molecular basis for sex differences in occurrence and outcome of brain tumors, using both mouse models and patient-derived tissue samples, with the goal of developing effective treatments for childhood brain tumors.  His work as been continuously supported by funding from the government and foundations and has resulted in more than 55 peer-reviewed publication.  His expertise has been recognized by appointments as Chair of the Scientific Advisory Board of the Children’s Brain Tumor Foundation, as Organizer of Project Renew: Restoring Cognition in Children with Brain Tumors, and as a member of many NIH study sections and scientific advisory boards.  His educational contributions include serving on more than thirty scholastic oversight and thesis committees, three as advisor, and training more than a dozen graduate students and postdoctoral fellows, including Karen Gauvain and David Limbrick, who have joined the faculty at Washington University.  In addition to his stellar contributions in the field of research and education, he was also ranked among the Top 10 Percent of Washington University Faculty on patient satisfaction surveys.

David Wilson, MD, PhD is promoted to Professor of Pediatrics in the Division of Hematology and Oncology.  After completing a BA in Chemistry at Kalamazoo College, MI, he came to Washington University for an MD and PhD followed by his residency in pediatrics at Boston Children’s and fellowship in Hematology/Oncology at Dana Farber Cancer Institute.  He returned to Washington University where he has been on the faculty since 1992.  He served as Director of the Division of Pediatric Hematology/Oncology for six years and as Co-Leader of the Develpmental Biology and Genetics Research Unit for another six years.  He lists bone marrow failure and coagulation disorders among his areas of particular clinical interest.  His research accomplishments include the cloning and characterization of GATA4, a transcription factor of importance in regulation of cardiac, endoderm, and gonadal development, and identifying GATA4 mutations as a cause of congenital diaphragmatic hernia and primary lung defects.  His lab also studies the effects of GATA 4 and GATA6 on differentiation of steroidogenic cells of the adrenal cortex and gonads.  He has published more than 90 manuscripts, 25 invited articles, and 16 book chapters.  Dr. Wilson’s educational contributions include training more than 20 students and post-docs and serving on numerous scholastic oversight and thesis committees.

Avraham Beigelman, MD, MSCI, is promoted to Associate Professor of Pediatrics in the Division of Allergy and Pulmonary Medicine.  After earning his undergraduate and medical degrees at Faculty of Health Sciences, Ben-Gurion University of the Negev, Beer-Sheva, Israel, followed by an Internship at Shaare Tzedek Medical Center, The Hebrew University, Jerusalem, Israel, and Residency in Pediatrics at Soroka Medical Center, Ben-Gurion University of the Negev, Beer-Sheva, Israel, Dr. Beigelman came to Washington University for fellowship in the Division of Pediatric Allergy, Immunology and Pulmonary Medicine.  Since joining the faculty he has also completed a Master of Science in Clinical Investigation.  He is active in the American Academy of Asthma, Allergy and Immunology, serving on several committees and as Vice- Chair of the Infections and Asthma Committee.  As an educator, he has twice been awarded “best lecture of the month” by the SLCH residents.  His scholarly work focuses on the inception and the potential prevention of childhood asthma, and includes several projects funded by the NIH and Children’s Discovery Institute in the areas of asthma and the relationship of microbiome in the airway to pediatric lung disease. He has been an active investigator in multiple NIH funded asthma research networks investigating therapeutic approaches to childhood asthma. He has twenty-eight peer reviewed publications reporting his work.  He serves a Clinical Director of the Food Allergy Program.

Caroline K. Lee, MD, is promoted to Associate Professor of Pediatrics in the Division of Cardiology.  Following her undergraduate degree at Wellesley College, Dr. Lee earned her MD at the University of Virginia School of Medicine, where she also completed a residency in Pediatrics.  She then completed fellowships in Pediatric Cardiology at Baylor College of Medicine in Houston, TX and Children’s National Medical Center in Washington, DC.  She is Director of Fetal Cardiology and has served as Associate Director of the Pediatric Cardiology Fellowship Program.  Her educational efforts also include numerous lectures for local and regional CME programs as well as mentorship of many cardiology fellows.  She teaches the introductory pediatric cardiology lectures in the Pathophysiology course at the School of Medicine, and regularly teaches fetal cardiology to both cardiology and maternal-fetal medicine fellows.  Her clinical interests include leading the High-Risk Cardiac Infant Interstage Monitoring Program and the Cardiac Neurodevelopmental Program.  Dr. Lee also serves on the Task Force for Critical Congenital Heart Disease for the Missouri Department of Health and Senior Services.

Charles Eldridge, IV, MD, is promoted to Assistant Professor of Pediatrics in the Division of Emergency Medicine.  After completing his BS at the University of Michigan in Ann Arbor, he graduated from Wayne State University School of Medicine, then served his Residency in Pediatrics at Children’s Hospital of Michigan in Detroit.  He came to Washington University in St. Louis School of Medicine as a Fellow in Pediatric Emergency Medicine, then joined the faculty.  He is Associate Fellowship Director for Pediatric Emergency Medicine and active in simulation where his responsibilities include developing and running simulations for the PEM fellows along with joint PEM-Surgery trauma simulations.  His educational contributions include helping to develop a Fellows Bootcamp for first year Pediatric Emergency Medicine Fellows that has been attended not only by Fellows at Washington University in St. Louis, but also by those from Cardinal Glennon, Detroit, Denver, Milwaukee, Kansas City and Austin.


Chesney Castleberry, MD is appointed as Assistant Professor of Pediatrics in the Division of Cardiology.  She comes to Washington University from the University of Cincinnati where she was Assistant Professor in the Division of Pediatric Cardiology. Dr. Castleberry earned her BS at Texas A&M and her MD at the University of Texas Medical School at San Antonio.  Following a pediatrics residency at Children’s Memorial Hospital at Northwestern University, Dr. Castleberry was a fellow in Pediatric Cardiology at Medical College of Wisconsin, and an Advanced Fellow in Heart Failure and Transplant at Stanford University.  Dr. Castleberry’s clinical expertise is in the field of pediatric heart failure and transplantation, including management of patients on mechanical circulatory support.  She is attending in the Heart Failure, Transplant, and Cardiomyopathy Clinic, and on the Inpatient Heart Failure and Transplant Service.  Her scholarly interests in include work with the Pediatric Cardiomyopathy Registry and Pediatric Heart Transplant Study Group.  She received the Transplant Early Career Award by the International Society for Heart and Lung Transplantation.  She has published six manuscripts including two review articles in the area of pediatric heart transplant.


Work-Life Balance


Retirement Medical Savings Account

An RMSA can be thought of as a Roth IRA for retiree health care. It is a trust or custodial account established exclusively to receive after tax contributions on behalf of eligible active faculty and staff to be used for retiree health care expenses. Earnings on the amounts contributed accumulate on a tax-free basis and are not subject to tax if they are used to pay for eligible medical expenses for employees and their dependents after the employee retires. Eligible expenses include retiree health plan premiums, Medicare premiums, long term care premiums and out-of-pocket health expenses after retirement.


Phased Retirement

To assist tenured faculty members in making an orderly transition to retirement, the University offers a Phased Retirement Program (“Program”) which includes a choice of two phased retirement plans. The mutual goal of these plans is to offer tenured faculty members the opportunity to take advantage of a period of reduced service during which the faculty member may begin withdrawing from departmental administrative obligations while continuing to teach, perform clinical responsibilities, and/or conduct research on a reduced schedule, and, as appropriate, to promote an orderly conclusion to graduate thesis supervisory duties.

More details

Summer Time for the Kids

Have you begun the search for summer camps for your children?  The St.Louis Post Dispatch has teamed with Blueprint4Summer STL to provide a database of thousands of camps which can be searched by interest, location, age etc.

Go to blueprint4summer.com to begin planning your summer.